The Centers for Disease Control and Prevention (CDC) is informing public health officials, clinicians, and affected patients, their families, and caregivers about a potential public health risk among individuals ordering what they believe to be prescription medications from online pharmacies. On September 30, 2024, the U.S. Department of Justice (DOJ) announced an indictment against individuals running illegal online pharmacies. According to the DOJ, these individuals are advertising, selling, manufacturing, and shipping millions of unregulated counterfeit prescription pills to tens of thousands of individuals in the U.S. The counterfeit pills frequently contain fentanyl, a synthetic opioid that is up to 50 times stronger than heroin and 100 times stronger than morphine, and methamphetamine. Individuals who ordered drugs from these illegal pharmacies could be at risk for an overdose.

The U.S. Food and Drug Administration warns that there are online pharmacies that claim to sell prescription drugs at deeply discounted prices, often without requiring a prescription. These internet-based pharmacies often sell unapproved, counterfeit, or otherwise unsafe medicines outside the safeguards followed by licensed pharmacies. Individuals should only take medications prescribed by a licensed healthcare provider and dispensed by a licensed pharmacy.

According to the National Association of Boards of Pharmacy, nearly 95% of websites offering prescription-only drugs online operate illegally.